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Scientific thinking about weight control

        SCIENTIFIC THINKING ABOUT WEIGHT CONTROL
Traditional thinking: The physics model. It has always been thought that the main causes of excess body fat are simply too little exercise and/or too much food. The traditional model for defining this has been encompassed by the formula:
Change in energy stores = Energy intake (EI) - Energy Expenditure (EE)
Where EI = calories from food, EE = resting metabolic rate (MR) + thermogenesis + daily physicalactivity.
There are now a number of reports that have established this is clearly inadequate for describing weight gains and losses in living organisms. According to the above calculation, for example, it has been estimated that a 75kg man who is in energy balance and who then adds an extra slice of toast and butter (100kcal) a day to his diet for 40 years would gain around 189kg over that time—a prediction which is clearly not sensible. The discrepancy results because energy is more closely balanced in free living organisms than was once thought. This comes about because there are changes in EE and EI with changing weight (e.g. changes in metabolic rate and the energy cost of activity, or changes in food intake with changes in physical activity). The above formula then needs to be modified to reflect rates of change, thereby allowing for the effects of changing energy stores on energy expenditure. It is now clear that initial differences between EI and EE (such as a modest increase in total calorie intake) do not lead to unbounded changes in body mass, hence the insufficiency of the physics approach.

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